Disruption of Apaf1 leads to defective craniofacial development in the mouse embryo
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چکیده
منابع مشابه
Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death.
Centromere protein C (CENPC) is a key protein that has been localized to the inner kinetochore plate of active mammalian centromeres. Using gene targeting techniques, we have disrupted the mouse Cenpc gene and shown that the gene is essential for normal mouse embryonic development. Heterozygous mice carrying one functional copy of the gene are healthy and fertile, whereas homozygous embryos fai...
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15 صفحه اولThe Role of Glycoconjugates in Development of Floor Plate During Early Morphogenesis in Mouse Embryo
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2010
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2010.05.127